HD Desktop is an integrated software platform designed specifically to enhance the analysis of hydrogen/deuterium exchange (HDX) mass spectrometry data. Building upon the codebase of The Deuterator, it integrates tools for data extraction with visualization components within a single web-based application. The interface design enables users to navigate from the peptide view to the sample and experiment levels, tracking all manipulations while updating the aggregate graphs in real time. HD Desktop is integrated with a relational database designed to provide performance enhancements, as well as a robust model for data storage and retrieval. Designed to address broad needs of the HDX community and continue the previous work, the platform presented here provides an efficient and manageable workflow for HDX data analysis and is freely available as a web tool for non-commercial purposes. 

Additional information is available from the publication

For support issues and questions please email hdadmin@scripps.edu

If you use this software in a publication, please cite: Pascal, B.D., Chalmers, M.J., Busby, S.A., Griffin, P.R. HD Desktop: an integrated platform for the analysis and visualization of H/D exchange data. Journal of the American Society for Mass Spectrometry 2009 Apr;20(4):601-10. Epub 2008 Dec 6.

Coming soon! HDX WorkBench building on the work from HD Desktop, we have developed a new application which facilitates automation, management, visualization and statistical cross-comparison of large HDX data sets. Great emphasis was placed on achieving three main goals of increased analysis speed; user-friendly graphic interface; and strong support for large HDX data sets. Using the software, validated data analysis can be achieved at the rate of generation. This software will be made available at this web site in May of 2012.

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